How Much Do Genes Matter?

Children with a parent who has a specific chronic health condition are at least 100% more likely to have the same condition themselves. To assess the role of genetic mechanisms in generating these strong correlations, I estimate models using a sample of approximately 2,400 adoptees, and find that genetic transmission accounts for only 20%-30% of the baseline associations.

Paper. HT: Jason Shafrin.

17 thoughts on “How Much Do Genes Matter?”

    1. It’s amazing to think that our ancestors survived so many things to get where we are

  1. “For instance, many chronic conditions appear or are exacerbated by lifestyle considerations such as patient diet and exercise habits.”

    Which will only make it worse

  2. Epigenetics also plays a role in gene expression. Past studies of identical twin siblings have looked at differences in diseases and conditions for people with the same genetic makeup. For instance, one women may get breast cancer even though her identical twin sister doesn’t. Scientists are now searching for reasons why one gene expresses itself. The answer is often environment.

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